4-Guanidinobutanoic acid-N3

4-Guanidinobutanoic acid-N3/4-Guanidinobutanoic acid-Azide is a multifunctional click chemical intermediate with guanidine, carboxyl, and azide groups simultaneously. As a bifunctional linker, it couples with alkynyl/DBCO modified biomolecules through azide groups, introducing positively charged guanidine units on the molecule to regulate its cell penetration performance. As a small molecule probe, by clicking on reaction markers such as proteins and nucleic acids, and introducing guanidine tags, it enhances the specificity and efficiency of subsequent target enrichment.

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